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Proton density fat fraction

The proton density fat fraction, measured by magnetic resonance imaging (MRI-PDFF), provides an accurate, validated marker of hepatic steatosis; however, it is not clear whether the PDFF identifies patients at risk for NAFLD progression proton density fat-fraction (PDFF), which is defined as the ratio of density of mobile protons from fat (triglyc-erides) and the total density of protons from mobile triglycerides and mobile water. The PDFF is a funda-mental property of tissue and reflects the concentra Background: To study the spatial heterogeneity of liver fat fraction changes during a long-term lifestyle intervention study using magnetic resonance imaging (MRI). Methods: Thirty-two subjects underwent two MRI-scans in a span of one year. A chemical shift encoding-based water-fat separation method was applied to measure liver proton density fat fraction (PDFF) maps Author information: (1)Department of Radiology, University of California at San Diego, 408 Dickinson St, San Diego, CA 92103-8592, USA. PURPOSE: To compare the accuracy of several magnetic resonance (MR) imaging-based methods for hepatic proton-density fat fraction (FF) estimation at 3.0 T, with spectroscopy as the reference technique

MRI proton-density fat fraction (PDFF) is a chemical shift iamging based water and fat separation technique. R2* (1/T2*) can be acquired in several seconds breath-hold, and the PDFF images can be used to calculate the fat fraction (FF) Proton density fat fraction (PDFF) calculation is a recently described (24 - 27) chemical shift-based water and fat separation technique that can be performed by magnitude and complex-based techniques MR Spectroscopy-derived Proton Density Fat Fraction Is Superior to Controlled Attenuation Parameter for Detecting and Grading Hepatic Steatosis Jurgen Henk Runge, Loek Pieter Smits, Joanne Verheij, Annekatrien Depla, Sjoerd Douwe Kuiken, Bert Cornelis Baak, Aart Johannes Nederveen, Ulrich Beuers, Jaap Stoke Proton density fat fraction (PDFF) was assessed over all vertebral levels for six human cadavers between 53 and 92 years of age, based on fat and water MR images

Magnetic Resonance Imaging Proton Density Fat Fraction

Markers are needed to predict progression of nonalcoholic fatty liver disease (NAFLD). The proton density fat fraction, measured by magnetic resonance imaging (MRI-PDFF), provides an accurate, validated marker of hepatic steatosis; however, it is not clear whether the PDFF identifies patients at risk for NAFLD progression. We performed a follow-up study of 95 well-characterized patients with. Dive into the research topics of 'Magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) is a viable alternative to liver biopsy for steatosis quantification in living liver donor transplantation'. Together they form a unique fingerprint

Dive into the research topics of 'Magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) is a viable alternative to liver biopsy for steatosis quantification in living liver donor transplantation'. Together they form a unique fingerprint. Living Donors Medicine & Life Sciences Fatty Liver Medicine & Life Science Calimetrix PDFF (Proton-Density Fat-Fraction) Phantoms are designed for testing and quality control of magnetic resonance (MR)-based fat quantification. PDFF phantoms are available in both spherical housing and phantom pack configurations. Spherical PDFF Phantom Feature positioning. HISTO provides Proton Density Fat Fraction (PDFF) that has been corrected for fat and water transverse relaxation. Since this is a spin echo sequence R2 values are provided rather than R2* values (R2* is calculated from GRE sequences). The color bar map will show fat at the top in percent and R2 water wit Proton Density Fat Fraction (PDFF) PDFF has been widely shown to correlate with the degree of hepatic steatosis, with a cut-off of 5% being indicative of NALFD; The only regulatory cleared MRI method capable of reporting a steatosis grading. Volumetric Liver Fat Fraction (VLFF MREplus+ automatically generates an intuitive summary of the analysis, with images showing ROIs and tabulated values for any combination of liver stiffness, proton density fat fraction, and T2* data. The summary of the analysis is designed to be suitable for sharing with referring physicians along with the radiologic report

• Assess the volumetric liver fat fraction, proton density fat fraction and steatosis grade in individuals with confirmed or suspected fatty liver disease; When interpreted by a trained physician, the results can be used to • monitor liver fat content in patients undergoing weight loss management and can be used t Proton density fat-fraction is an accurate biomarker of hepatic steatosis in adolescent girls and young women. Eur Radiol 2015; 25:2921-2930 [Google Scholar] 23. Bannas P, Kramer H, Hernando D, et al. Quantitative MR imaging of hepatic steatosis: validation in ex vivo human livers Objectives To evaluate proton density fat fraction (PDFF) and T2* measurements of the liver with combined parallel imaging (sensitivity encoding, SENSE) and compressed sensing (CS) accelerated chemical shift encoding-based water-fat separation. Methods Six-echo Dixon imaging was performed in the liver of 89 subjects. The first acquisition variant used acceleration based on SENSE with a total. To investigate multi-echo chemical shift-encoded MRI-based mapping of proton density fat fraction (PDFF) and fat-corrected R2* in bone marrow as biomarkers for osteoporosis assessment. Fifty-one patients (28 female; mean age 69.7 ± 9.0 years) underwent dual energy X-ray absorptiometry (DXA). On the basis of the t score, 173 valid vertebrae bodies were divided into three groups (healthy.

Proton Density Fat-Fraction: A Standardized MR-Based

Longitudinal changes on liver proton density fat fraction

  1. ed the.
  2. Quantification of pancreatic proton density fat fraction in diabetic pigs using MR imaging and IDEAL-IQ sequence. Chen Y(1), Long L(2), Jiang Z(1), Zhang L(1), Zhong D(1), Huang X(1). Author information: (1)Radiology Department, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China
  3. Magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) is a viable alternative to liver biopsy for steatosis quantification in living liver donor transplantation. Qiaochu Qi, Internal Medicine Program, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA
  4. Measurement of the liver fat fraction has become possible by measuring proton density fat fraction (PDFF) using MR imaging [13,14]. The purpose of the current study was to evaluate whether PDFF measured by MR imaging (MRI-PDFF) correlates with histological pancreatic fat fraction and its possible usefulness as a biomarker of pancreatic cancer.
  5. Texture analysis (TA) has shown promise as a surrogate marker for tissue structure, based on conventional and quantitative MRI sequences. Chemical-shift-encoding-based MRI (CSE-MRI)-derived proton density fat fraction (PDFF) of paraspinal muscles has been associated with various medical conditions including lumbar back pain (LBP) and neuromuscular diseases (NMD)

The study evaluates four physically motivated constraints in the estimation of the proton density fat fraction (PDFF). Least squares approaches were developed for constraining the parameters in PDFF quantification based on the physics of magnetic resonance imaging. These were smooth fieldmap, smooth initial phase, nonnegative proton density and. Purpose. This study aims to compare the accuracy of proton-density fat fraction (PDFF) measurements with chemical shift magnetic resonance imaging (CSI) for quantifying the fat content of adrenal nodules and for differentiating adenomas from nonadenomas

MRI-Proton Density Fat Fraction Treatment Response Criteria in Nonalcoholic Steatohepatitis NASH is one of leading causes of chronic liver disease in the United States.(1) NASH can lead to cirrhosis, end-stage liver disease, and hepatocellular car - cinoma and has become one of the leading indications for liver transplant in the United States The proton density fat fraction (PDFF, the frac-tion of the liver proton density attributable to liver fat) measurement is a recently developed advanced MRI-based technique for quantita-tive assessment of hepatic steatosis. MRI-PDF Accuracy of MR imaging-estimated proton density fat fraction for classification of dichotomized histologic steatosis grades in nonalcoholic fatty liver disease. Radiology 274 , 416-425 (2015)

Objective This study evaluated the diagnostic performance of the proton density fat fraction (PDFF) in predicting the progression of osteoporotic vertebral compression fractures (OVCFs). Methods The cohort in this retrospective study consisted of 48 patients with OVCFs who underwent spine MRI that included PDFF between December 2016 and June 2018. The patients were divided into two groups. Background Clinical or biochemical markers that have good correlation with magnetic resonance proton density fat fraction (MR PDFF) can be used as simple tools for the screening for nonalcoholic fatty liver disease (NAFLD) and in determining the degree of fatty infiltration of the liver. The objective of this study was to determine the degree of relationship between MR PDFF and ultrasonography. Proton-density fat fraction measurement: A viable quantitative biomarker for differentiating adrenal adenomas from nonadenomas. [en] Highlights: • PDFF differentiated adenomas from nonadenomas with high sensitivity and specificity. • PDFF measurements are simple and can be readily applicable in clinical practice The recently developed magnetic resonance imaging (MRI) proton density fat fraction (PDFF) allows measurement of the fat in all segments of hepatic tissue. However, it is time consuming and inconvenient to measure each segment repeatedly. Moreover, volume of each segment also should be adjusted with arithmetic mean of the selected segments when total amount of liver fat is estimated

Proton density fat fraction (PDFF), based on chemical-shift-encoded magnetic resonance imaging (CSE-MRI), is a validated non-invasive quantitative imaging biomarker for hepatic fat content [1,2,3,4,5,6,7,8].It has demonstrated excellent repeatability and reproducibility and is also accurate for quantifying fat content, using either histology or MR spectroscopy as reference standards [9,10,11] related to the proton density fat fraction (PDFF) and water T2 (T2w) determination as imaging markers for fatty infiltration and edematous alterations, respectively. Specifically, PDFF is defined as the ratio of density from mobile triglyceride protons and total density from mobile triglycerides and mobile water [35] We compared CAP with the M vs the XL probe for quantification of hepatic fat content, using magnetic resonance imaging proton density fat fraction (MRI-PDFF) as the standard. METHODS: We performed a prospective study of 100 adults (mean body mass index [BMI], 30.6±4.7 kg/m2) with and without NAFLD, assessed by CAP with the M probe and XL probe. Proton density fat fraction calculation for MRI. Contribute to marcsous/pdff development by creating an account on GitHub (2019). Noninvasive monitoring of hepatic steatosis: controlled attenuation parameter and magnetic resonance imaging-proton density fat fraction in patients with nonalcoholic fatty liver disease. Expert Review of Gastroenterology & Hepatology: Vol. 13, No. 6, pp. 523-530

Estimation of hepatic proton-density fat fraction by using

Fat fraction quantification and assessment of its distribution in the hepatic tissue become more important with the growing epidemic of obesity, and the increasing prevalence of diabetes mellitus type 2 and non-alcoholic fatty liver disease. At 3Tesla, the multi-echo, chemical-shift-encoded magnetic resonance imaging (CSE-MRI)-based acquisition allows the measurement of proton density fat. We assessed the diagnostic performance of magnetic resonance imaging (MRI) proton density fat fraction (PDFF) in grading hepatic steatosis and change in hepatic steatosis in adults with nonalcoholic steatohepatitis (NASH) in a multi-center study, using central histology as reference

Boxplot shows MRI-based PDFF values and the corresponding

Proton-density fat fraction measurement: A viable

We investigated the ability of attenuation imaging (ATI) to detect steatosis that was identified by proton density fat fraction (PDFF) on magnetic resonance imaging (MRI) in patients with chronic liver disease. Methods. A total of 119 patients with chronic liver disease (non-B, non-C) were analyzed. The relationship between ATI values and. the liver proton density fat fraction (PDFF) (10). However, single-voxel MRS has limited spatial coverage as it typically reports the result on one specific area of the liver per measurement. Therefore, neither biopsy nor single-voxel MRS can cover the whole liver and therefore cannot detect any heterogeneity in liver fat deposition. In addition QIBA Proton Density Fat Fraction Biomarker Committee (PDFF BC) Update Call Thursday, November 7th, 2019 at 3 p.m. (CT) Call Summary Participants RSNA Scott Reeder, MD, PhD (Co-chair) Joe Diego Hernando, PhD Nancy Obuchowski, PhD Koudelik Takeshi Yokoo, MD, PhD (Co-chair) Harry Hu, PhD Suraj Serai, PhD Susan Stanfa Gavin Hamilton, Ph

Dapagliflozin plus saxagliptin add‐on to metformin reduces

Hepatic Steatosis: Quantification by Proton Density Fat

  1. ed proton density fat fraction (PDFF) or MRE value and attenuation coefficients were evaluated. In addition, the interaction between hepatic.
  2. al DECT and abdo
  3. g increasingly accessible. Previous studies have tended to use multiple small ROIs that focus on Couinaud segments. In an effort to simplify day-to-day analysis, this study assesses the impact of using larger, elliptical ROIs focused on a single hepatic lobe
  4. Patients with nonalcoholic fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH) often require histologic assessment via liver biopsy. Magnetic resonance imaging (MRI)-based methods for measuring liver triglycerides based on proton density fat fraction (PDFF) are increasingly used as a noninvasive tool to identify patients with hepatic steatosis and to assess for change in liver.
  5. Furthermore, as the proton density in fat is not equal to the proton density of liver tissue there is a non-linear relationship between the liver fat volume fraction and the fat : water proton ratio. Hence, a 5 percent change in fat : water proton ratio does not equate to a 5% change of fat in the liver
  6. MRI-derived proton density fat fraction (PDFF) is a technique that accurately quantifies the hepatic fat content and has been accepted as an alternative to the histological assessment of liver steatosis in patients with NAFLD . MRI-PDFF is not influenced by confounding factors, including body weight, and is operator independent . However, it.

MR Spectroscopy-derived Proton Density Fat Fraction Is

  1. 28. Johnson BL, Schroeder ME, Wolfson T, et al. Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging 2014; 39:440-447 [Google Scholar
  2. ation of imaging markers such as the proton density fat fraction (PDFF). The present work aims to assess the diagnostic value of PDFF in correlation to Mercuri grading and clinically deter
  3. ate on conventional MRI alone and was misdiagnosed as bone metastasis after additional review of PDFF maps by both readers
  4. ation repeatability of magnetic resonance spectroscopy, magnitude-based MRI, and complex-based MRI for estimation of hepatic proton density fat fraction in overweight and obese children and adults. Abdom Imaging. 2015 Oct;40(8):3070-7. doi: 10.1007/s00261-015-0542-5

The purpose of this study was to evaluate the added value of proton density fat fraction (PDFF) in differentiating vertebral metastases from focal hematopoietic marrow depositions. MATERIALS AND METHODS. The study included 44 patients with 30 vertebral metastases and 14 focal hematopoietic marrow depositions who underwent spinal MRI article is to compare 2 alternatives: Proton-Density-Fat-Fraction (PDFF) MRI and MultiMaterial-Decomposition (MMD) DECT. Materials and Methods: 49 consecutive oncologic patients treated with Chemotherapy underwent abdominal DECT and abdominal MRI within 2 weeks of each other We assessed the performance of magnetic resonance imaging (MRI) proton density fat fraction (PDFF) in children to stratify hepatic steatosis grade before and after treatment in the Cysteamine Bitartrate Delayed-Release for the Treatment of Nonalcoholic Fatty Liver Disease in Children (CyNCh) trial, using centrally scored histology as reference Introduction:Oncologic patients who develop chemotherapy-associated liver injury (CALI) secondary to chemotherapy treatment tend to have worse outcomes. Biopsy remains the gold standard for the dia..

Proton density fat fraction of the spinal column: an MRI

Among the cadre of these noninvasive biomarkers, MRI‐proton density fat fraction (MRI‐PDFF) is one of the leading imaging‐based biomarkers of assessing antisteatotic benefits of a drug therapy in NASH. MRI‐PDFF is a precise, reproducible, and accurate imaging‐based biomarker of liver fat quantification Proton density fat-fraction: a standardized MR-based biomarker of tissue fat concentration. J Magn Reson Imaging 2012; 36 : 1011-1014. Article PubMed PubMed Central Google Schola

Video: Standardized Approach for ROI-Based Measurements of Proton

techniques (CSE-MRI) have proven to be reliable for determination of proton density fat fraction (PDFF) (19-21) with some concomitant advantages. In contrast to 1H-MRS, the entire volume of an organ can be assessed within a short measurement time (<20 s, i.e. in a single breath-hold) with good spatial resolution, allowing The proton density fat fraction, measured by magnetic resonance imaging (MRI-PDFF), provides an accurate, validated marker of hepatic steatosis; however, it is not clear whether the PDFF identifies patients at risk for NAFLD progression. We performed a follow-u Short-term variability of proton density fat fraction in pancreas and liver assessed by multi-echo chemical-shift encoding-based MRI at 3 T. Jürgen Machann, Maytee Hasenbalg, Julia Dienes, Robert Wagner, Arvid Köhn, Andreas L. Birkenfeld, Konstantin Nikolaou, Stephanie Kullmann, Fritz Schick, Martin Heni This study aims to investigate how fat is distributed throughout the spinal column to confirm or refute the suitability of lipid content for guidance purposes. Results Proton density fat fraction (PDFF) was assessed over all vertebral levels for six human cadavers between 53 and 92 years of age, based on fat and water MR images

MRI‐Proton Density Fat Fraction Treatment Response

Quantification of pancreatic proton density fat fraction in diabetic pigs using MR imaging and IDEAL-IQ sequence Yidi Chen, Liling Long*, Zijian Jiang, Ling Zhang, Delin Zhong and Xialing Huang Abstract Background: Recent studies have highlighted the correlation between diabetes and pancreatic fat infiltration pancreatic fat measurements [13,14]. Among the various MRI-based methods for fat quantification, proton density fat fraction (PDFF) is considered the most practical and objective because the fat fraction can be obtained quantitatively by separating water and fat using a chemical shift technique [15]. I Proton density fat fraction (PDFF) estimated by MRI is a noninvasive biomarker of hepatic steatosis1 MRI-PDFF correlates with histologic grade of hepatic steatosis2 ≥ 30% relative decrease in PDFF has been associated with a histologic response in NASH2,3 Selonsertib (SEL; formerly GS-4997) is a selective inhibitor o

Constraints in estimating the proton density fat fraction

It is possible to estimate hepatic triglyceride content by calculating the proton density fat fraction (PDFF), using proton magnetic resonance spectroscopy (1H-MRS), instead of collecting and analyzing liver biopsy specimens to detect steatosis. However, the current PDFF cut-off value (5%) used to define steatosis by magnetic resonance was derived from studies that did not use histopathology. PDFF, proton density fat fraction; PG, parotid gland; STEAM, stimulated echo acquisition mode. The 95% confidence interval for the slope was 0.96 to 1.14. The 95% confidence interval for the intercept was −5.83 to 1.70 The easiest way to identify proton density (PD) fat saturated images is to look for adipose tissues in the body (e.g. subcutaneous fat and fat in bone marrow). Areas contain adipose tissues appear as dark on PD fat saturated images. All other characteristics of the PD fat saturated images remain same as the PD image proton density fat fraction (PDFF) analysis. 4,5 Furthermore, IgG4-related dacryoadenitis and sialadenitis (IgG4-DS) was recently recognized as an independent entity from SS because of its clinical and serological features. The salivary function is either normal or improved with the adminis

a Photographic image of phantoms containing different percentages of fat (0, 5, 10, 15, 20, 30, 40, and 50).b Image showing the proton density fat fraction using the multiecho Dixon technique. The fat volumes in each phantom were determined for a Gd-EOB-DTPA concentration of 0 mM and for a Gd-EOB-DTPA concentration of 0.4 mM. The tags show the average proton density fat fraction for five scans. Proton-density fat fraction and simultaneous R2* estimation as an MRI tool for assessment of osteoporosis. Kühn JP , Hernando D , Meffert PJ , Reeder S , Hosten N , Laqua R , Steveling A , Ender S , Schröder H , Pillich DT. Eur Radiol, 23 (12):3432-3439, 29 Jun 2013 Version 1.0 Date: 3.28.18 fraction, MRI-PDFF techniques measure the proton density fat-fraction - the fraction of the liver proton density attributable to liver fat - which is a fundamental. Pancreatic fat infiltration may be associated with several diseases involving the pancreas, including type 2 diabetes, pancreatitis, pancreatic cancer, cystic fibrosis, haemochromatosis [1, 2], and vertebral body density fat fraction [].The role of pancreatic fat infiltration in the pathogenesis of type 2 diabetes has been increasingly emphasized, such that the relationship between pancreatic. Proton density fat fraction, T1, T2, and were measured repeatedly during cooling on ice. Temperature corrections were derived from these measurements for the parameters that showed significant.

Quantitative MRI Assessment of Pancreatic Steatosis Using

Magnetic resonance imaging-derived proton density fat

MRI-Proton Density Fat Fraction Treatment Response Criteria in Nonalcoholic Steatohepatiti Currently, the accepted quantitative MR biomarker for fat content is the proton-density fat fraction (PDFF) in percent [40], defined as the ratio between MR-observable fat protons and all MR. Research Article Diagnostic Value of MRI Proton Density Fat Fraction for Assessing Liver Steatosis in Chronic Viral C Hepatitis Francesco Paparo,1 Giovanni Cenderello,2 Matteo Revelli,3 Lorenzo Bacigalupo,1 Mariangela Rutigliani,4 Daniele Zefiro,5 Luca Cevasco,3 Maria Amico,6 Roberto Bandelloni,4 Giovanni Cassola,2 Gian Luca Forni,7 and Gian. Yokoo T, Shiehmorteza M, Hamilton G et al (2011) Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. Radiology 258:749-759. PubMed Article PubMed Central Google Scholar 19

Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis Michael S. Middleton,1 Elhamy R. Heba,1 Catherine A. Hooker,1 Mustafa R. Bashir,2 Kathryn J. Fowler,3 Kumar Sandrasegaran,4 Elizabeth M. Brunt,3 David E. PURPOSE: Chemical shift-encoded MRI (CSE-MRI) is well-established to quantify proton density fat fraction (PDFF) as a quantitative biomarker of hepatic steatosis. However, temperature is known to bias PDFF estimation in phantom studies. In this study, strategies were developed and evaluated to correct for the effects of temperature on PDFF. Proton-density fat fraction and simultaneous R2* estimation as an MRI tool for assessment of osteoporosis. Download. Proton-density fat fraction and simultaneous R2* estimation as an MRI tool for assessment of osteoporosis. Peter Meffert. Diego Hernando. Antje Steveling. Norbert Hosten. Jens-Peter Kühn

Both models use the radiofrequency ultrasound signals as the input and use the MRI-proton density fat fraction (PDFF) as the reference (labels). In the case of the classifier, NAFLD is defined as MRI-PDFF >= 5%. livernet_1d_cnn.py contains the final model architecture for both the classifier and the fat fraction estimator

General 1 — Calimetri

This study was undertaken to explore the role of three-dimensional Fat Analysis & Calculation Technique sequence in improving the diagnostic accuracy for the detection of osteopenia and osteoporosis by simultaneous quantification of proton density fat fraction (PDFF) and fat-corrected R2∗ Purpose: To evaluate the influence of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) on proton density fat fraction (PDFF) using multiple vendors' DIXON methods in a multicenter, multivendor phantom study. Materials and Methods: Pairs of phantoms with varying fat volume percentages (0, 5, 10, 15, 20, 30, 40, and 50) and Gd-EOB-DTPA concentrations (0 and 0.4 mM. Pancreatic proton density fat fraction (P-PDFF) was measured as the average value for three circular regions of interest (ROIs) drawn in the pancreatic head, body, and tail. Age, weight, laboratory results, and mean liver MRI values including liver PDFF (L-PDFF), stiffness on MR elastography, and T2 * values were assessed for their correlation.

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17. Chen Y, Jiang Z, Long L, et al. Magnetic resonance imaging: proton density fat fraction for assessment of pancreatic fatty infiltration during progression of T2DM bama minipigs. J Magn Reson Imaging. 2019;50:1905-1913 OBJECTIVE. The purpose of this study was to evaluate the reproducibility (interreviewer agreement) and repeatability (intrareviewer agreement) of ROI sampling strategies to measure chemical shift-encoded (CSE) MRI-based liver proton density fat fraction (PDFF) and R2* (1 / T2*). A secondary purpose was to standardize ROI-based liver PDFF and R2* measurements by providing a compromise between. Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis. Gastroenterology 2017;153:753-61. Submitted Oct 27, 2017. Accepted for publication Apr 11, 2018. doi: 10.21037/hbsn.2018.04.0

MR Spectroscopy–derived Proton Density Fat Fraction Is(PDF) Accuracy of MR Imaging–estimated Proton Density Fat